High-dose vitamin C on sepsis: Protocol of a prospective, multi-centered, double-blinded, randomized, and placebo-controlled superiority study
BackgroundSepsis is an inflammatory syndrome with life-threatening organ dysfunction and high mortality.In the recent 10 years, high-dose intravenous injection of vitamin C, the first-line antioxidant of humans, has received highlighted attention in the field of critical care.The Pillows study aims to examine the efficacy and safety of high-dose in